Wanting to save the house of her beloved grandmother from being sequestered, paranormal expert Carmel Monseratt (Kim Chiu) and her “bebest” best friend Jerald “Jeje” Zee-Yan (Ryan Bang) have decided to form a squad of ghost busters with their misfits buddies Bagang (Pepe Herrera), Ponzi (Lassy Marquez), and Basha (Moi Bien) in order to meet both ends. 

One day, when they no longer have customers due to their modus going viral, Carmel meets a rich architect and dashing eligible bachelor Jack Colmenares (Enzo Pineda) who wants her and her squad to exorcize his house of all the ghosts inside it – real malevolent ghosts! – in exchange of a hefty amount of money

Despite the fear, Carmel and Jeje together with their squad accept the job offer as their last act. Little do they know this will lead to all of them being entrapped inside Jack’s house with extremely pesky and spiteful ghosts, screaming & running for their lives, and with Carmel ultimately facing the horror of the truth long hidden from her.